Cerebral blood flow (CBF)

Dr Craig Hacking and A.Prof Frank Gaillard et al.

Cerebral blood flow (CBF) is one of the parameters generated by perfusion techniques (CT perfusion and MR perfusion). CBF is defined as the volume of blood passing through a given amount of brain tissue per unit of time, most commonly milliliters of blood per minute per 100g of brain tissue 1.

In most instances cerebral blood flow is difficult to measure in absolute terms, and relative CBF (rCBF) is calculated instead; relative to normal white matter

Quantitative CBF (qCBF) can be estimated using specific techniques, and varies significantly between white and grey matter (roughly twice as high in grey vs white matter)  2

  • grey matter: ~50 +/- 15 ml/100g/min *
  • white matter: 22 +/- 5 ml/100g/min

* these are rounded figures as differences exist between techniques and publications

Physics and Imaging Technology: MRI
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Article information

rID: 43779
Synonyms or Alternate Spellings:
  • CBF

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Cases and figures

  • Figure 1: CBF
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  • Figure 2: perfusion parameters
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