Clinically unclassifiable parkinsonism

Clinically unclassifiable parkinsonism (CUP) is a term applied to patients who have some parkinsonism features, but who do not fulfill clinical criteria for a particular disorder such as:

Some measures have been investigated and found to be useful in predicting evolution from CUP to PSP, e.g. Magnetic Resonance Parkinsonism Index (MRPI) or midbrain to pons area ratio.

Neurodegenerative diseases

Neurodegenerative diseases are legion and their classification just as protean. A useful approach is to divide them according to underlying pathological process, although even using this schema, there is much overlap and thus resulting confusion.

Share article

Article information

rID: 28839
Tag: refs, cases
Synonyms or Alternate Spellings:
  • Clinically unclassifiable parkinsonism (CUP)
  • CUP
  • Parkinsonism

Support Radiopaedia and see fewer ads

Updating… Please wait.

 Unable to process the form. Check for errors and try again.

 Thank you for updating your details.