Lesions of the corpus callosum (differential)

Lesions of the corpus callosum are uncommon and arise from multiple different etiologies. The lesions can be classified according to underlying pathophysiology 4-6.


Typically, amongst neoplasms, only aggressive lesions can invade the corpus callosum as it is composed of very dense white matter tracts which act as a barrier to tumor spreading 1.

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Article information

rID: 18622
Section: Gamuts
Tag: refs
Synonyms or Alternate Spellings:
  • Corpus callosal mass
  • Mass involving the corpus callosum
  • Callosal lesions
  • Corpus callosum mass
  • Corpus callosal masses
  • Corpus callosal lesions

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Cases and figures

  • Case 1: primary CNS lymphoma
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  • Case 2: glioblastoma
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  • Case 3: GBM involving the splenium
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  • Case 4: probable Marchiafava-Bignami
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  • Case 5: cavernous malformation
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  • Case 6: infarct
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