N-acetylaspartate (NAA) peak

N-acetylaspartate (NAA) is one of the more important compounds assessed on MR spectroscopy, and resonates at 2.0 ppm chemical shift. 

NAA is the acetylated form of the amino acid, aspartate, which is found in high concentrations in neurons and is a marker of neuronal viability. It is therefore reduced in any process that destroys neurons, such as high grade tumors, radionecrosis, non-neuronal tumors (e.g. cerebral metastases and primary CNS lymphoma).

MR spectroscopy
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Article information

rID: 27827
Section: Physics
Tag: stub, refs
Synonyms or Alternate Spellings:
  • N-acetylaspartate peak
  • N-acetylaspartate (NAA)

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