Ovarian mucinous tumors

Dr Henry Knipe and Radswiki et al.

Ovarian mucinous tumors are a subgroup of ovarian epithelial tumors. They represent 10-15% of all ovarian tumors and ~10% of all malignant ovarian tumors. They are subdivided according to their malignant potential and clinical behavior into:

More common in women aged 20-50 years old 6.

On histology they show multiple cysts lined by mucinous epithelium, often resembling gastrointestinal-type epithelium 6. KRAS mutations are a common feature.

Mucinous ovarian tumors can be broadly subclassified into three main subgroups:

In general, the cell type (e.g. serous, mucinous) often cannot be determined by the appearance on imaging 5. While some of the specific features can vary between the subtypes, there are certain features which are more common among mucinous tumors: 3

  • often larger than their serous counterparts (on occasion they may be enormous)
  • tend to be more multilocular with small cystic components +/- honeycomb-like locules
  • calcification is comparatively rare and if present tends to be linear
  • usually unilateral
  • peritoneal carcinomatosis is less common compared with serous tumors
  • may have accompanying pseudomyxoma peritonei
  • T1
    • signal intensity of locules varies depending on the degree of mucin concentration
    • loculi with watery mucin have a lower signal intensity than loculi with thicker mucin
  • T2
    • the above-mentioned corresponding signal intensities are flipped so that loculi with watery mucin have a higher signal intensity and loculi with thicker mucin appear slightly hypointense
    • the combination of locules with different signal intensities may result in a "stained glass appearance"

Prognosis of mucinous tumors is highly dependent on the stage and histologic composition: see individual subtypes for further details. Primary treatment is surgical unless there is extra-ovarian disease 6.

  • ovarian serous tumors
    • tend to be unilocular  
    • often smaller than mucinous tumors
    • more frequently bilateral  
    • calcifications (psammoma calcifications) 
  • hemorrhagic cyst
    • smaller
    • unilocular
    • resolves on a follow-up scan
  • endometrioma
    • high signal on T1 weighted images with T2 shading (signal characteristics typical of blood products)
Ultrasound - gynaecology
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Article information

rID: 15034
System: Gynaecology
Synonyms or Alternate Spellings:
  • Mucinous tumours of the ovary
  • Mucinous ovarian tumours
  • Mucinous ovarian tumors
  • Ovarian mucinous tumours
  • Ovarian mucinous tumors
  • Ovarian mucinous neoplasm
  • Ovarian mucinous neoplasms

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Cases and figures

  • Case 1: ovarian mucinous cystadenoma
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  • Case 2: ovarian mucinous cystadenoma
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  • Case 3: unknown ovarian mucinous neoplasm
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  • Case 4: ovarian cystadenocarcinoma
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