Rocky mountain spotted fever

Rocky mountain spotted fever (RMSF), also known as Brazilian spotted fever, is an infectious disease caused by Rickettsia rickettsii which are usually transmitted by infected ticks bites. 

RMSF distribution correlates with the presence of its vectors, and has been identified the United States of America and in many parts of Central and South Americas, and generally is a notifiable disease in most of the countries 2

There is a classical triad of nonspecific symptoms which are not always present 1

  • fever
  • headache 
  • rash

The symptoms are in general similar to viral syndromes and the epidemiological features are essential to better direct the diagnosis 1.

Serological analysis by immunofluorescence reaction can be used as sensitive method to diagnosis rickettsioses, however the PCR method is known as more useful as it can discriminate the different species of Rickettsia 1.

Rickettsia rickettsii is a Gram-negative coccobacillus and is an obligate intracellular bacterium 1-2.

Humans are known as accidental hosts. 

Infections of the central nervous system
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Article information

rID: 39530
Synonyms or Alternate Spellings:
  • Brazilian spotted fever
  • Febre maculosa

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