Transitional cell carcinoma grading

Transitional cell carcinomas of the urothelium are graded histologically as follows:

  • transitional cell papilloma
    • benign tumor, not a carcinoma but sometimes included in classification systems
  • carcinoma in situ
    • do not penetrate the basement membrane
    • cells resemble those of grade II or III tumors
  • grade I: low grade, rarely invade deeply or metastasize
  • grade II: intermediate grade
  • grade III: high grade, aggressively invasive with early metastases

It is important to note that grade is not as important in establishing prognosis as is stage 2.

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Article information

rID: 2199
System: Urogenital
Tag: bladder
Synonyms or Alternate Spellings:

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