Wyburn-Mason syndrome (also known as Bonnet-Dechaume-Blanc syndrome) is a rare, nonhereditary neurocutaneous disorder that typically presents with unilateral vascular malformations that primarily involve the brain, orbits and facial structures. It is currently classified as a craniofacial arteriovenous metameric syndrome (CAMS) 3-4.
- facial vascular nevus
- visual pathway and orbital arteriovenous malformations (AVMs)
- intracranial arteriovenous malformations (AVMs)
Cases of bilateral malformations have been described and there is an association with subarachnoid hemorrhage.
History and etymology
- Roger Wyburn-Mason (1911-1983), British neurologist at the National Hospital of Neurology and Neurosurgery (Queen Square), London
- Paul Bonnet (1894-1959), French ophthalmologist
- Jean Dechaume (1896-1968), French neurosurgeon
- Eugene Blanc (1888-1961), French neurosurgeon
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