Advanced frontotemporal atrophy, predominantly involving the high frontal lobes (the superior and middle frontal gyri) with markedly thinned cortex with loss of normal grey white differentiation. The mesial temporal lobes are less severely involved but there is slight asymmetrical involvement of the left greater than right anterior temporal pole.
No gross abnormality of the brainstem, in particular no mid brain atrophy. No intra or extraaxial mass, haemorrhage or infarction. Perfusion study demonstrates decreased bifrontal CBV.
Advanced frontotemporal atrophy, overall pattern favouring frontotemporal dementia.