Chronic myeloid leukemia - MRI

Case contributed by Dr Chris O'Donnell


Low back pain

Patient Data

Age: 84
Gender: Male

Bone marrow is diffusely of dark signal on T1 and high on STIR, apart from the Modic type II changes in the L5/S1 endplates. This indicates conversion or infiltration of normal yellow (fatty) marrow. 

Spleen is markedly enlarged.


Case Discussion

Always look at the vertebral body signal on MRI scanning of the spine as it may be the first clue to bone marrow pathology.  Review of medical history in this case confirmed that the patient had CML for many years.

Spleen is markedly enlarged as occurs in CML.

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Case information

rID: 16804
Published: 21st Feb 2012
Last edited: 21st Sep 2015
System: Haematology
Tag: spine
Inclusion in quiz mode: Included

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