L-asparaginase induced pancreatitis in childhood acute lymphoblastic leukemia

Case contributed by Dr Sajoscha Sorrentino


Patient with childhood acute lymphoblastic leukemia with elevated amylase and lipase.

Patient Data

Age: 10
Gender: Male

Enlarged pancreas and peripancreatic fluid in the lesser sac and left pararenal space. 

Case Discussion

L-asparaginase has been part of the treatment of childhood onset ALL for many decades now. L-asparaginase induced pancreatitis is known to be a major complication of this treatment, but the pathophysiology behind this is still to be found. 

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Case information

rID: 20164
Published: 5th Nov 2012
Last edited: 14th Aug 2019
Inclusion in quiz mode: Included

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