Articles

Articles are a collaborative effort to provide a single canonical page on all topics relevant to the practice of radiology. As such, articles are written and edited by countless contributing members over a period of time. A global group of dedicated editors oversee accuracy, consulting with expert advisers, and constantly reviewing additions.

66 results found
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Abdominoschisis

Abdominoschisis refers to a split or defect in the abdominal wall. Some authors use the term synonymously with a gastroschisis. When the defect continues into the thoracic region it is termed a thoraco-abdominoschisis. A large abdominoschisis is considered part of the limb body wall complex 2. ...
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Abnormally thickened endometrium (differential)

Abnormally thickened endometrium on imaging may occur for a number of reasons which may be categorized based on whether or not they are related to pregnancy. Etiologies may also be classified based on whether the patient is premenopausal or postmenopausal. Differential diagnosis Pregnancy-rela...
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Absent fetal stomach on ultrasound (differential)

Non-visualization of the fetal stomach on ultrasound can occur with various physiological as well as pathological processes. It becomes a significant sonographic observation >14 weeks of gestation (about the time the fetus begins to swallow). Causes include: physiological emptying: transient ...
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Absent septum pellucidum

An absent septum pellucidum may rarely be an isolated finding, or more commonly be seen in association with a variety of conditions. Epidemiology The septum pellucidum is partly or entirely absent in 2 or 3 individuals per 100,000 in the general population.  Pathology An absent septum pelluc...
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Acute abdominal pain

Acute abdominal pain is a common acute presentation in clinical practice. It encompasses a very broad range of possible etiologies and diagnoses, and imaging is routinely employed as the primary investigative tool in its modern management. Terminology A subgroup of patients with acute abdomina...
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Alpha fetoprotein

Alpha fetoprotein (AFP) is an important plasma protein synthesized by the yolk sac and fetal liver. In adults its main utility is as a tumor marker, primarily for hepatocellular carcinoma or teratoma. Functionally it is the fetal homologue of albumin, i.e. it acts as a major carrier protein in t...
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Bands in gestational sacs

Band like structures in the gestational sac is not an uncommon finding in the first trimester or second ultrasounds and can represent a number of varying conditions These include uterine synechiae amniotic bands amniotic shelf circumvallate placenta chorio-amniotic separation velamentous ...
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Beta-hCG

Beta-hCG (bHCG or β-hCG) is a sex hormone found in the mother's blood serum that can be used to help interpret obstetric ultrasound findings. Beta-hCG levels may be used in three ways in the clinical setting of pregnancy: qualitatively, for presence/absence of fetal tissue more often determin...
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Birth trauma

Birth trauma relates to those conditions caused by both physical/mechanical and hypoxic injuries. Epidemiology Birth trauma occurs in ~5 per 1000 births 2. Risk factors asphyxia breech presentation shoulder dystocia instrument delivery macrosomia obstructed labor Pathology Etiology T...
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Cervical incompetence

Cervical incompetence refers to a painless spontaneous dilatation of the cervix and is a common cause of second trimester pregnancy failure. Epidemiology The estimated incidence varies geographically and generally thought to be around 1-1.5% of all pregnancies 1,15. Clinical presentation Typ...
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Congenital limb amputation

Congenital limb amputation is the absence of a fetal limb or part of a limb that usually occurs due to disruption of vascular supply. Epidemiology Congenital amputations occur in 0.5 (range 0.03-1) per 1000 live births 2.  Pathology They are slightly more common in the upper limb (60%) than ...
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Congenital renal anomalies

Congenital renal anomalies comprise of vast spectrum of pathologies and include: renal agenesis renal dysgenesis congenital renal hypoplasia congenital megacalyectasis congenital cystic renal disease infantile polycystic renal disease: autosomal recessive polycystic kidney disease (ARPKD):...
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Differential diagnosis for bleeding in pregnancy

Uterine bleeding during pregnancy is a common clinical presentation that often necessitates obstetric ultrasound for the assessment of the hemorrhage, and of fetal well being. The potential causes vary with the stage of gestation. Bleeding in the first trimester miscarriage threatened miscar...
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Dystocia of shoulder

Shoulder dystocia (SD) refers to the failure of the shoulder to be delivered during childbirth and the need for extra-obstetric maneuvers to facilitate their passage after normal smooth gentle downward traction has failed. Dystocia literally means difficult labor. Epidemiology The incidence of...
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Echogenic fetal lung lesions

Echogenic fetal lung lesions on antenatal ultrasound can be detected in a number of situations. They include: Airway obstructions: lung are often enlarged and echogenic bilaterally congenital high airways obstruction syndrome (CHAOS) tracheal atresia congenital tracheal stenosis laryngeal a...
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Empty gestational sac

Empty gestational sacs can be due to a number of causes: anembryonic pregnancy (also known as "blighted ovum") early pregnancy (intrauterine): by 5.5 weeks gestational age, a yolk sac should be identifiable by transvaginal ultrasound pseudogestational sac with an ectopic pregnancy gestationa...
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Enlarged echogenic fetal kidneys

Enlarged echogenic fetal kidneys can be associated with a number of pathologies that include: autosomal recessive polycystic kidney disease (ARPKD) 1 autosomal dominant polycystic kidney disease (ADPKD) 3: the large cysts may not form in utero and the kidneys may initially appear as enlarged a...
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Failed early pregnancy

Failed early pregnancy refers to the death of the embryo and therefore, miscarriage. The most common cause of embryonic death is a chromosomal abnormality. Radiographic features Ultrasound Findings diagnostic of pregnancy failure crown-rump length (CRL) of ≥7 mm and no heartbeat on a transva...
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Fetal anterior abdominal wall defects

Fetal anterior abdominal wall defects can occur with a number of pathologies. Individual entities omphalocele gastroschisis cloacal exstrophy bladder exstrophy Syndromes/complexes limb body wall complex OEIS complex omphalocele-radial ray (ORR) complex Pentalogy of Cantrell amniotic ...
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Fetal ascites

Fetal ascites refers to the accumulation of free fluid in the fetal abdomen. It is often considered under the same spectrum of hydrops fetalis. Pathology Etiology any condition that results in hydrops fetalis additional causes include idiopathic bowel perforation (e.g. meconium peritonitis...
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Fetal biophysical profile

Fetal biophysical profile score (BPS or BPP) refers to assessment of four discrete biophysical variables by ultrasound. It is a standard tool in antepartum fetal assessment. It is usually assessed after 28 weeks of gestation. Radiographic features Antenatal ultrasound The ultrasound variables...
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Fetal bowel dilatation

Fetal bowel dilatation can occur from many causes, which include: intestinal atresias: mainly distal anal atresia apple-peel intestinal atresia ileal atresia jejunal atresia jejuno-ileal atresia Hirschsprung disease megacystis microcolon hyperperistalsis syndrome 4 congenital chloride d...
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Fetal brain tumors

Fetal brain tumors are uncommon and tends to have very different pathological spectrum than that observed in adults; in order of decreasing frequency: fetal intracranial teratoma: most common tumor by far astrocytoma/glioblastoma: next most common craniopharyngioma: papillary type primitive ...
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Fetal cardiac tumors

Fetal cardiac tumors refer to primary cardiac tumors that can present in the in utero population.  Epidemiology Fetal cardiac tumors are rare; the prevalence, reported from autopsy studies of patients of all ages, varies from 0.0017-0.28 % 2. Pathology Known cardiac tumor types that present ...
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Fetal chylothorax

Fetal chylothorax is defined as the presence of lymphatic fluid within the pleural cavity of the fetus. Pathology Associations pulmonary hypoplasia hydrops fetalis premature delivery Radiographic features Antenatal ultrasound may show echogenic fluid in the pleural cavities Treatment S...
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Fetal clenched hands

Fetal clenched hands are an antenatal ultrasound observation where the fetal hands are in a constant (permanently) clenched position as if being unable to extend. Pathology Some authors 3 suggest  that the abnormal posture results in part from: muscle variations along the radial margin of the...
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Fetal death in utero

Fetal death in utero (FDIU), also known as intrauterine death (IUD), is the term used when the death of a fetus occurs after the 20th week of pregnancy. Prior to this, it is considered a miscarriage. Epidemiology 1% of normal, uncomplicated pregnancies end in fetal death. In ~15% of FDIU, no c...
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Fetal intra-abdominal cysts (differential)

Fetal intra-abdominal cystic lesions can arise from a number of physiological and pathological causes. Physiological fetal gastric dilatation / fetal gastric bubble (can be pathological if there is a gastric outlet obstruction normal fetal gallbladder Pathological No color flow fetal chole...
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Fetal intracranial calcification

Fetal intracranial calcification refers to intracranial calcification detected in utero. This can arise from a number of pathologies which include: in utero infections fetal toxoplasmosis infection: calcification tends to be randomly distributed fetal cytomegalovirus infection1: calcificatio...
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Fetal intracranial cystic lesions

Fetal intracranial cystic lesions can arise from a number of pathologies, including: Non-tumourous fetal arachnoid cyst  fetal choroid plexus cyst fetal connatal cyst fetal porencephalic cyst fetal interhemispheric cyst fetal subependymal cyst dorsal cyst of holoprosencephaly Blake pouc...
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Fetal intracranial hemorrhage

Fetal intracranial hemorrhage may occur either within the cerebral ventricles, subdural space or infratentorial fossa. Pathology Hemorrhages can occur in a number of situations: mechanical trauma, e.g. maternal abdominal blunt or birth trauma severe fetal hypoxia background fetal thrombocyt...
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Fetal intrahepatic calcification

Fetal intrahepatic calcification can be a relatively common finding. Calcifications in the liver can be single or multiple and in most cases in which isolated hepatic calcific deposits are detected, there is usually no underlying abnormality. The presence of isolated intrahepatic calcification ...
Article

Fetal limb bowing

Fetal limb bowing may be a feature of skeletal dysplasia, particularly if it is severe. A mild degree of lateral bowing of the femur can occur as part of normal variation. Conditions associated with fetal limb bowing include: campomelic dysplasia 1 thanatophoric dysplasia 2: particularly type...
Article

Fetal pleural effusion

Fetal pleural effusions (FPE) refer to an accumulation of pleural fluid in utero. It can refer to either a fetal chylothorax or a fetal hydrothorax. Pathology A fetal pleural effusion can occur as part of hydrops fetalis, in association with other anomalies without hydrops or in isolation - pr...
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Fetal pyelectasis

Fetal pyelectasis refers to a prominence of the renal pelvis in utero that is a relatively common finding, which in the majority of cases resolves spontaneously.  Please refer to the article on fetal hydronephrosis for a continued discussion on this matter.  Terminology  Although there is an ...
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Fetal rib fractures

Fetal rib fractures can be caused by certain skeletal dysplasias. These include: osteogenesis imperfecta: type II - one of the classical causes of fetal rib fractures achondrogenesis: type Ia - Houston-Harris sub type
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Fetal tumors

Although rare, a number to tumors may be diagnosed antenatally. These fetal tumors are a diverse and a unique group of conditions, and include: neuroblastoma: most common tumor overall teratomas sacrococcygeal teratoma head and neck teratoma/epignathus mediastinal teratoma intrapericardial...
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Fetal ventriculomegaly (differential)

Fetal ventriculomegaly (ventricle width >10 mm) is an important finding in itself and it is also associated with other central nervous system abnormalities. For more information, see the main article fetal ventriculomegaly. Differential diagnosis Fetal ventriculomegaly can be thought of in ter...
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Frontal bossing

Frontal bossing is a calvarial radiographic feature where the front of the skull appears protruding anteriorly. It is best appreciated on a sagittal or lateral image. Pathology This feature can be seen in many conditions (in alphabetical order): 18q syndrome acromegaly achondroplasia ß-tha...
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Gonadal dysgenesis

Gonadal dysgenesis refers to a spectrum of anomalies with abnormal development of the gonads. It falls under the even broader group of disorders of gender development. Pathology In many cases the gonads are replaced by fibrous tissue. Subtypes complete gonadal dysgenesis (CGD) / Swyer syndro...
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Hypotelorism

Hypotelorism refers to an abnormal decrease in distance between any two organs although some authors use the term synonymously with orbital hypotelorism meaning an abnormal decrease in the distance between the two eyes (the eyes appear too close together). The article mainly focuses on the latte...
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Intracranial cystic lesions in the perinatal period

Intracranial cystic lesions in the perinatal period can carry a relatively wide differential which includes: Supratentorial cystic lesions cysts arachnoid cyst choroid plexus cyst connatal cyst holoprosencephaly multicystic encephalomalacia periventricular leukomalacia porencephalic cys...
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Intrauterine contraceptive device

Intrauterine contraceptive devices (IUCD) are one of the most frequently used methods of contraception throughout the world. It prevents pregnancy by: thinning the endometrial lining preventing sperm motility preventing implantation There are two main types of IUCDs: non-hormonal metallic (...
Article

IUCD related uterine perforation

IUCD (Intrauterine contraceptive device) related uterine perforations are one of the causes of uterine perforation. It is rare, but a serious complication of an IUCD insertion, and is often clinically silent.  Epidemiology The incidence rate is reported at ~2 in 1000 2. Clinical presentation ...
Article

Large for dates uterus

A large for date uterus is a clinical observation based on uterine fundal height, which may result in referral for ultrasound assessment, usually in mid to late pregnancy.    Causes include: incorrect dates constitutionally large fetus multiple pregnancy fetal macrosomia polyhydramnios ut...
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Narrow fetal thorax

A narrow fetal thorax on antenatal ultrasound can be present with a number of anomalies which include: achondrogenesis campomelic dysplasia homozygous achondroplasia Jarcho-Levin syndrome Jeune syndrome - asphyxiating thoracic dysplasia Russell-Silver dwarfism short rib polydactyly syndro...
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Oligohydramnios

Oligohydramnios refers to a situation where the amniotic fluid volume is less than expected for gestational age. Often these fetuses have <500 mL of amniotic fluid. Epidemiology The estimated prevalence can be up to ~6% of pregnancies 4. Pathology Causes The causes of oligohydramnios are pr...
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Perigestational hemorrhage

Perigestational hemorrhage refers to hemorrhage that occurs around the fetus during the gestational period. The spectrum of hemorrhage includes: chorionic hemorrhage: caused by the separation of the chorion from the endometrium  subchorionic hemorrhage: most common type, occurs between the cho...
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Placentomegaly

Placentomegaly is a term applied to an abnormally enlarged placenta.  Pathology Associations It can be associated with a number of maternal and fetal disorders which include: maternal maternal anemia(s) maternal diabetes chronic intrauterine infections alpha-thalassemia fetal umbilical...
Article

Polyhydramnios

Polyhydramnios refers to a situation where the amniotic fluid volume is more than expected for gestational age. It is generally defined as: amniotic fluid index (AFI) >25 cm largest fluid pocket depth (maximal vertical pocket (MVP)) greater than 8 cm 6: although some centers, particularly in ...
Article

Pregnancy of uncertain viability

Pregnancy of uncertain viability (PUV) is a term given to an intrauterine pregnancy in a situation where there are not enough criteria (usually on ultrasound grounds) to confidently categorize an intrauterine pregnancy as either viable or a failed pregnancy.  Radiographic features Ultrasound ...
Article

Rhizomelic dwarfism

Rhizomelic dwarfism is a type of dwarfism where the dominant feature is proximal (i.e. femoral, humeral) limb shortening. Pathology The following conditions fall under the heading of rhizomelic dwarfism 3 metatropic dysplasia achondrogenesis rhizomelic chondrodysplasia punctata achondropla...
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Shortened fetal femoral length

Shorted fetal femur is a morphological descriptor and is usually defined when the femoral length falls below the 5th centile for gestational age (some define it when it is under the 2.5th centile 5) or less than 0.91 predicted by the bi-parietal diameter. It can occur in isolated or in associati...
Article

Shortened fetal humerus

Shortened fetal humerus is a morphological description and is usually defined when the humeral length falls below the 5th percentile or less than 0.9 as predicted by the biparietal diameter (BPD). It can occur in isolation or in association with a number of other anomalies. The humeral length i...
Article

Short umbilical cord

Short umbilical cord has been variably defined. Considering the mean length of the umbilical cord is 50-70 cm 1-2, a short cord in absolute terms is usually taken as one that is under 35-40 cm in length at term 1-2.  Pathology Associations Recognized associations include chromosomal anomalie...
Article

Skeletal dysplasia

Skeletal dysplasia (also known as osteochondrodysplasia) refers to any abnormality in bone formation. There is a very wide clinicopathological spectrum and any part of the skeleton can be affected. Epidemiology The overall prevalence is estimated at ~2 per 10,000 live births 3. Pathology Typ...
Article

Small for date fetus

A small for dates fetus can result from a number of factors Fetal factors aneuploidy trisomy triploidy skeletal dysplasia(s) structural anomalies (syndromes) Maternal factors Common hypertension medication(s): fetal Warfarin syndrome hydantoin embryopathy (Dilantin TM) cytotoxic dru...
Article

Small placenta

A small placenta if observed on antenatal ultrasound can arise from a number of situations. They include: variation in placental morphology: where only part of the placenta is seen bilobed placenta: with only one lobe seen succenturiate lobe: with either main lobe or succenturiate lobe not se...
Article

Sonographic values in obstetrics and gynecology

Obstetric and gynecological ultrasound is rampant with numerous cut off values. Some of these get revised over the years. The following list is a useful aid to refer to and revise. 1 mm rate of increase of a mean sac diameter per day in early pregnancy 2 mm generally accepted value for a thi...
Article

Spinal Dysraphism

Spinal dysraphism is a broad term given to a group of anomalies where there are malformations in the dorsum of the embryo. Neural tube defects come under this group as well.  Pathology The neural tube is formed by the lengthwise closure of the neural plate, in the dorsum of the embryo. The up...
Article

Syndactyly

Syndactyly (plural: syndactylies) refers to a congenital fusion of two or more digits. It may be confined to soft tissue (soft tissue syndactyly/simple syndactyly) or may involve bone (bony syndactyly/complex syndactyly). Epidemiology The overall estimated incidence is at ~1 per 2,500 to 5,000...
Article

Threatened miscarriage

Threatened miscarriage (or threatened abortion) is mainly a clinical term, used when a pregnant woman in first 20 weeks of gestation presents with spotting, mild abdominal pain and contractions, with a closed cervical os.  Epidemiology It occurs in 20-25% of pregnancies and is associated with ...
Article

Trauma in pregnancy

Trauma is a leading cause of mortality in pregnancy. Pregnancy increases the incidence and severity of abdominal trauma in females.  Epidemiology Trauma affects up to 7% of pregnancies, and the incidence of pregnancy in level 1 trauma patients is estimated to be ~2% 1.  Pathology Etiology 9...
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Twin pregnancy

Twin pregnancies are the most common multifetal pregnancies.  Epidemiology Multifetal pregnancies account for ~ 1% of all pregnancies but are seen in much higher numbers in populations where in vitro fertilisation (IVF) is a common practice, most of which are twin pregnancies. Classification ...
Article

Umbilical cord cyst

Umbilical cord cysts can refer to any cystic lesion associated with the umbilical cord. They can be single (commoner) or multiple. Epidemiology They may be seen in ~3% of pregnancies in the first trimester 8. Pathology Umbilical cord cysts can represent either true or false cysts: true cyst...
Article

Uterine enlargement (differential)

Uterine enlargement can occur in a number of situations from both diffuse and focal processes. These include:  gestation related events normal intrauterine pregnancy molar pregnancy - gestational trophoblastic disease  postpartum uterus - still larger than usual hormonal causes exogenous h...

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