Diffuse alveolar hemorrhage - Goodpasture syndrome


Diagnosis of Goodpasture syndrome was established with a renal biopsy showing anti-glomerular basement membrane antibody.

This disease is more common in men than women and hemoptysis is a dominant clinical symptom.

Differentials for airspace opacification, such as in this case, would include:

  • diffuse pulmonary hemorrhage:
    • Goodpasture syndrome, Wegner granulomatosis, systemic lupus erythematosus, Behçet syndrome, bleeding diatheses, among others
  • infection (atypical, such as PCP, influenza)
  • non-cardiogenic pulmonary edema