Silicosis: eggshell calcification

Discussion:

Main causes of lymph node calcification:

  • benign
    • tuberculosis
    • histoplasmosis
    • sarcoidosis
    • silicosis
    • coal worker's pneumoconiosis
    • amyloidosis
  • malignant
    • ​treated lymphoma and metastases

Aids to differentiating cause: silicosis vs sarcoidosis vs tuberculosis

  • calcified lymph nodes in tuberculosis tend to affect the mediastinum asymmetrically and unilaterally
  • diffuse bilateral lymph node involvement is more common in sarcoidosis
  • silicosis: the patient usually has a history of a silica-exposure related job (as it was in this case)
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